HALIX offers GMP mammalian cell culturing and protein production from recombinant sources
Therapeutic proteins are one of modern medicines most powerful inventions. They are used to treat a great variety of clinical indications (e.g. cancers, autoimmune disorders, infectious agents and genetic disorders). Protein based therapeutics meet unmet medical needs and improve standard of care therapies.
The first therapeutic proteins were extracted from the bodies of animals and humans or made in fermentation by utilizing naturally producing microorganisms. Modern biopharmaceuticals are typically made using bacterial or mammalian cell culture and GMP bioreactor technology.
The Process of Protein Production
The process of protein manufacturing is highly challenging and specialized. Bioreactor based cell culturing requires tight control of all factors that may influence the yield, the quality or the potency of the produced drug substance. Proteins are generated through expression of transgenes in well characterized cell platforms.
HALIX has expertise in protein production using different cell types:
- Insect cells
- Mammalian cells (e.g. CHO and HEK 293 cell production)